On April 27, 2020, Axsome Therapeutics announced that AXS-05, a novel, investigational medicine intended for use in Alzheimer’s Disease, met the primary endpoint in its clinical trial. Alzheimer’s Disease is a type of neurological disorder which can result in a decline in memory and cognitive ability and is often associated with agitation. Axsome aims for AXS-05 to become an FDA-approved treatment for Alzheimer’s Disease agitation, for which there are currently no approved therapies. In clinical trials, AXS-05 was found to reduce the frequency of agitation-related behavior, such as restlessness and aggression, in patients with dementia, when compared to placebo. AXS-05 was well tolerated in the trial with drowsiness, dizziness, and diarrhea as the most commonly reported adverse events.